Clinical Research Office. A partnership between Sheffield Teaching Hospitals NHS Foundation Trust and the University of Sheffield

Efficient and Accurate Feasibility

Accurate feasibility is the first step in achieving delivery, and our robust systems ensure efficient and accurate feasibility assessment of all studies is undertaken.

Rapid determination of your needs

Our Patient History Integrated Datastore (PHInD), is designed to simplify the process of interrogating existing, deā€identified, clinical data for preliminary cohort discovery. If you have defined eligibility criteria for your clinical trial, PHInD can help determine the feasibility of your study.

  • We can discover how many patients within your demographic and clinical criteria have been seen in a given time period within our clinical directorates. This provides an excellent estimate of the number of patients you can expect to visit our hospitals and clinics
  • Exploring the impact of various search criteria – such as demographics, diagnostics, therapies, and procedures – on the size of the patient cohort will help us identify potential inclusion/exclusion issues and optimise your protocol design prior to regulatory submission
  • All of this allows us to rapidly determine whether we have sufficient patient population to deliver your study, before the study begins.

 

Feasibility review meeting

Numbers alone cannot replace experience. Whilst PHInD can give a good estimate of potential participants, issues such as demanding treatment regimens and placebo arms can have huge impact on the number of patients who choose to participate in a research study.

To ensure that all aspects of recruitment feasibility are assessed, all of our studies undergo a feasibility meeting attended by the principal investigator, specialist research nurse and research coordinator. The research coordinator is assigned to the project for the entire project duration and ensures continuity of study management as the project progresses.