Clinical Research Office. A partnership between Sheffield Teaching Hospitals NHS Foundation Trust and the University of Sheffield
Academic Directorate of Communicable Diseases and Specialised Medicine

 

The Academic Directorate of Communicable Diseases and Specialised Medicine comprises of five specialities:

  • Haematology
  • Dermatology
  • Immunology
  • Infectious Diseases
  • Sexual Health

 

Research and Innovation Strategy 2023-2026 

RI Strategy Copy (sth.nhs.uk)

 

The modulation of macrophage apoptosis during Streptococcus pneumoniae infection by HIV-1

The use of advanced lung function tests and a new type of scan that identifies Obstructive Lung Disease in people living with HIV- Dr Paul Collini

Key Contacts

Name

 Role                       

Dr Nicholas Morley Clinical Director - Haematology 
Dr Benjamin Stone
Clinical Director - Communicable Diseases     
Prof John Snowden Research Lead - CDSM
Dr Jack Goddard Research Lead - Haematology-Oncology
Dr Matthew Sims Research Lead - Haematology
Dr Claire Dewsnap Research Lead - Sexual Health and GUM
Dr Joby Cole Research Lead - Infectious Diseases
Dr Sarah Denness Research Lead - Immunology
Dr Sura Sahib Research Lead - Dermatology
Dr Eva Zincone eva.zincone@nhs.net Directorate Research Coordinator
Melanie Fox melanie.fox6@nhs.net Industry Research Coordinator
Adam Smith adam.smith78@nhs.net CRIO Research Coordinator
Grace Cole grace.cole1@nhs.net CRIO Research Coordinator (Haemato-Oncology)
Jekatarina Kudina jekatarina.kudina@nhs.net CDSM Research Administrator
Sth.CDSMresearch@nhs.net Please use this email for general enquiries

Communicable Diseases

The Communicable Diseases team focuses on the prevention and treatment of infectious diseases through behavioural modification, vaccination and preventive treatment. Since all sectors of society are at risk of infections these approaches impact the lives of all society. Moreover since many of the problems we tackle, such as HIV, hepatitis, influenza, enteric fever and pneumonia have global reach our research is relevant not just in the UK.

Specialised Medicine

The diverse specialties encompassed in the specialised medicine team address some of the most common disorders presenting to healthcare professionals within the NHS, ranging from  dermatological, immune and haematological disorders including cancer.

Haematology

 
Haemato-oncology
 
The Haematology Oncology team at Sheffield Teaching Hospitals is deeply committed to advancing clinical research, actively participating in numerous national and international studies.
 
Our Haemato-Oncology department is structured into three specialised sub-teams, each led by dedicated consultants with a focus on specific research areas:
 
  • Lymphoid Team - specialising in research on all lymphoid malignancies
  • Myeloma Team - advancing studies in the field of myeloma, with interest in autologous HSCT for myeloma, multiple myeloma and myeloma transplant
  • Myeloid Team - driving research in all myeloid disorders such as AML, MDS, Graft-vs-host disease.
 
Our collaborative efforts aim to improve outcomes for patients through innovative treatments and cutting-edge research.
 

BLOOD CANCER RESEARCH AT SHEFFIELD TEACHING HOSPITALS

 

 
 
 
Sheffield Teaching Hospitals are proud to be part of the IMPACT stem cell transplant clinical trials initiative. IMPACT is the UK's first ever clinical trials partnership dedicated to improving the outcomes of stem cell transplant patients.
 
 
Non-Malignant Haematology
 
The Haemophilia and Thrombosis Centre at Sheffield Teaching Hospitals are active in clinical research and are participating in national and international trials in the following areas:
 
Haemophilia and Bleeding Disorders
  • Novel non-factor haemophilia treatment
  • Gene therapy in haemophilia
  • Long-acting factor treatments for haemophilia
  • Joint disease in haemophilia
  • Genetics of rare bleeding conditions
 
Red Cell Disorders and Haemoblobinopathies
  • Sickle cell disease
  • Haemoglobinopathies (including Thalassemia and Sickle Cell)
  • Red Cell Disorders
 
Haemostasis and Thrombosis
  • Mechanisms of Haemostasis and Thrombosis
  • Advances in Clotting and Bleeding Management

 

Immunology
 
The Immunology research team at Sheffield Teaching Hospitals are interested in investigating Allergies and Hereditary Angiodema (HAE).
 

Our consultant Dr Ravishankar Sargur's most recent publications (updated September 2024):

  • Rejection of Fecal Immunochemical Tests Within the Lower Gastrointestinal Diagnostic Pathway: A Cohort Study. DOI:10.1177/21501319241228161

  • Evaluation of Cryoprotein Investigation Using A Digital External Quality Assurance Scheme. DOI:10.1177/00045632241239805

 
Dermatology
 
The dermatology research team at Sheffield Teaching Hospitals are very active in clinical research taking part in national and international trials in the following areas:
  • Psoriasis
  • Atopic dermatitis (Eczema)
  • Registry studies of patients receiving treatment for dermatological conditions
  • Alopecia