Motor Neuron Disease (MND) is a group of diseases with multiple causes. Thus, tailoring treatments for the different subtypes of MND may result in more effective therapies.
|
|
|
| With Genomic Medicine and Bioinformatics, we hope to identify more genetic risk factors to define more categories of MND. | We are working to develop physiological and imaging biomarkers for MND, to monitor disease progression and assess response to treatments. |
 |
_320x189.png) |
| Gene Therapy work at Sheffield has shown exciting translational promise, with pre-clinical work being developed into experimental medicine trials. | Our basic science teams have established cellular models of neurodegenerative diseases to research molecular targets for therapy. |
Research in the neuromuscular theme also encompasses work into Duchenne Muscular Dystrophy, Hereditary Spastic Paraparesis, and increasingly, Myasthenia Gravis. Sheffield Teaching Hospitals is proud to take part in multi-centre trials across the disease areas.
_700x79.png)
 Professor Pamela Shaw Theme Lead
Honorary Consultant Neurologist
|
 Dr Channa Hewamadduma Deputy Theme Lead
|
|
Professor Chris McDermott
.jpg) Consultant Neurologist
|
