Clinical Research Office. A partnership between Sheffield Teaching Hospitals NHS Foundation Trust and the University of Sheffield



Neurophysiology studies the measurement and evaluation of nervous system function rather than nervous system architecture.

The department of Clinical Neurophysiology at Sheffield Teaching Hospitals is staffed by neurophysiology consultants and clinical physiologists who specialise in tests for a range of Neurological disorders.

Our neurophysiology researchers are interested in the development of new techniques to diagnose and monitor neuromuscular disorders using electrophysiology and different forms of spectroscopy in both pre-clinical and clinical settings. At present, investigations that assess muscle are painful, invasive and expensive. Therefore the research investigators are conducting at Sheffield Teaching Hospitals to find simple, quick and pain free methods to identify and monitor muscle pathology is of great importance.

Other techniques used in neurophysiology research include:

· Nerve conduction studies (NCS) and electromyography (EMG)

· Evoked Potentials (EPs)

· Quantitative Sensory Testing (QST)

· Electroencephalography (EEG)

· Intraoperative Monitoring (IOM)


Meet the team

 Dr James Alix

Honorary Consultant Clinical Neurophysiologist